In a word, yes. The Richard Mueller novelisation of the film states that the 'Terror Dog' was specifically looking for Louis and that while it was aware of his shortcomings, he was its sole target
The terror-dog had made its way down the side of the building and
stepped through the bedroom window, shedding glass and broken mullions
like flies off armor plate. The quarry was close, the one with whom
the great transformational joining would be resolved. It was here,
within this very area, but not within this chamber itself. It sniffed
a few coats on the bed, then sprang to alertness as Louis Tully opened
the door. It is him, the guardian thought, but before it could
act, Louis tossed the coats over it and left, slamming the door behind
him. It is nearsighted, decided the guardian, shaking off the coats.
It is ugly, too, but I have my duty. It let loose a terrible roar.
Presumably he (like Dana) has been prepared for demonic possession by being in the vicinity of so much psychic energy. That would also explain why he's been buying headache tablets by the gross.
“I have acetylsalicylic acid but I get the generic from Walgreen’s
cause I can get six hundred tablets for thirty-five percent less than
the cost of three hundred of the name brand. Do you have a headache?”