At no point in the movie does Vader tell the Imperial officers that he believes Luke is on board the Falcon. I've not read the novel, but I do think we must only be concerned with the actual movie.
In the movies, it is made very clear that Vader can sense Luke's presence when Luke is nearby. In Star Wars he can sense the presence of Luke during the attack on the Death Star ("The Force is strong with this one", he says, in the combat above the Death Star).
And in Return of the Jedi, Vader detects Luke's presence on board the stolen Imperial Shuttle Tyderium, during the approach to the Moon of Endor.
So it is simply not possible to include a scene in TESB in which Vader can express uncertainty as to whether Luke is aboard the Falcon. That would have undermined a key part of the powers Vader has from the Force, upon which the events of Return of the Jedi will depend.
In the movie TESB, Vader's motive is very clear: he wants to capture Han and the Princess, because by torturing them he can send a message to Luke, via the Force, which will draw Luke to him. He knows they are Luke's friends. He knows Luke will sense their pain through the Force.
There is actually a scene, in Cloud City, of Han being tortured. Han is baffled as to why this is happening, because they ask him no questions. But we, the audience, seen Luke's reaction, far away on Dagobah, when he feels the danger which Han and Leia are in.
Vader is solely interested in the occupants of the Falcon because they are Luke's friends, and can be used to draw Luke into a trap. And in one scene, we see Vader obtaining the Emperor's permission to try to turn Luke or to kill him, so we know that the Emperor considers Luke a significant threat, one that must be neutralised.
Later, we learn too that Vader had also a hidden motive for desiring to find Luke, as he has come to realise that Luke is his son.