Gathering information on this topic isn't easy. Collider work (Hadron or otherwise) is a major hush-hush operation. Unfortunately I don't have Q clearance in the Pentagon (or any other clearance for that matter), but some advanced Googling skills have revealed that one of the prime collider ops involved the PPA (פפא) collider. Classic hadron sources typically refer to the members of the פפא team by codenames: Cha-9A, RAM-i, R. NachMN, R. AHA, Raf-RAM, ABA, Rach-ISH, Sur-HUB, ADA and Dr. U. The leader of the team is mentioned many times in the Talmud under the codename "R. PPA". There is one hint to the PPA team having managed to reach weapons-grade nuclear capabilities in a particular section in Brachot 58b:
"R. PPA and R. HUNA, son of RJ, were once walking along the road when they met R. Cha-9A the son of R. EAKA. They said to him: When we saw you we recited two blessings over meeting you: Blessed…Who has shared of His wisdom to those who revere Him, and: Who has given us life…as they had not seen him in over a month. He said to them: I too, once I saw you, considered you in my eyes as equivalent to six hundred thousand of the house of Israel, and I recited three blessings over you. I recited those two that you recited, as well as: Blessed…Who knows all secrets, which is the blessing recited upon seeing six hundred thousand Israelites. They said to him: Are you all that clever? They fixed their gaze upon him and he died.
The last sentence seems to refer to destructive nuclear capabilities unleashed by R. PPA and his mysterious partner, likely a foreign collaborator.